| Person | Type | Job | Role(s) | Episodes |
|---|---|---|---|---|
 Anson Williams | Crew | Directing | Director | 3 |
 Brenda Hampton | Crew | Production | Producer, Writer, Creator | 121 |
Gail Bradley | Crew | Directing | Director | 1 |
 Ron Underwood | Crew | Directing | Director | 2 |
 Alice Hirson | Cast | Actress | 1 | |
 Angela Bullock | Cast | Actress | Teacher | 1 |
 Annie Abbott | Cast | Actress | 1 | |
 Ben Weber | Cast | Actor | 3 | |
 Beth Grant | Cast | Actress | Victoria | 1 |
 Beverley Mitchell | Cast | Actress | Kaitlin O'Malley | 1 |
 Bianca Lawson | Cast | Actress | 3 | |
 Camille Winbush | Cast | Actress | 19 | |
 Cynthia Watros | Cast | Actress | 1 | |
 DeVaughn Nixon | Cast | Actor | Omar | 2 |
 Deborah Raffin | Cast | Actress | 1 | |
 Ernie Hudson | Cast | Actor | 3 | |
Jennifer Coolidge | Cast | Actress | Betty | 35 |
 Joseph C. Phillips | Cast | Actor | 1 | |
 Josie Bissett | Cast | Actress | Kathleen Bowman | 1 |
 Kathy Kinney | Cast | Actress | 4 | |
 Larry Sullivan | Cast | Actor | 4 | |
 Lauri Johnson | Cast | Actress | George's Mother | 1 |
 Mackenzie Rosman | Cast | Actress | 1 | |
 Mark Derwin | Cast | Actor | George Jeurgens | 1 |
 Mayim Bialik | Cast | Actress | Dr. Wilameena Bink | 1 |
 Molly Ringwald | Cast | Actress | Anne Juergens | 97 |
 Natalie Dreyfuss | Cast | Actress | Chloe | 1 |
 Nicholas Braun | Cast | Actor | Randy | 1 |
Rachel Grate | Cast | Actress | Marsha | 1 |
 Renee Olstead | Cast | Actress | 20 | |
 Rodney J. Hobbs | Cast | Actor | Eli | 1 |
 Rumer Willis | Cast | Actress | 1 | |
 Shailene Woodley | Cast | Actress | Amy Juergens | 121 |
 Shawnee Smith | Cast | Actress | Carrie | 2 |
 Steve Schirripa | Cast | Actor | Leo Boykewich | 74 |
 Tom Virtue | Cast | Actor | Reverend Stone | 1 |
 Amy Rider | Cast | Actress | Alice Valko | 121 |
 Christina Masterson | Cast | Actress | Random Girl | 1 |
 Cierra Ramirez | Cast | Actress | Kathy | 24 |
 Francia Raísa | Cast | Actress | Adrian Lee | 121 |
 India Eisley | Cast | Actress | Ashley Juergens | 97 |
 Ken Baumann | Cast | Actor | Ben Boykewick | 121 |
 Mallory Low | Cast | Actress | Debbie | 1 |
 Megan Park | Cast | Actress | Grace Bowman | 121 |
 Melise | Cast | Actress | Gail | 1 |
 Paola Turbay | Cast | Actress | 4 | |
 Reid Scott | Cast | Actor | 1 | |
 Valerie Tian | Cast | Actress | Wendy | 6 |
 Brando Eaton | Cast | Actor | 8 | |
 Brennan Mejia | Cast | Actor | Don | 2 |
 Daren Kagasoff | Cast | Actor | Ricky Underwood | 121 |
 Grant Harvey | Cast | Actor | Grant | 32 |
 Greg Finley | Cast | Actor | Jack Pappas | 121 |
 Jeanine Mason | Cast | Actress | Bebe | 1 |
 John DeLuca | Cast | Actor | Guy | 1 |
Matthew Levinson | Cast | John | 64 | |
 Michael Grant | Cast | Actor | Ethan | 24 |
Joseph Levinson | Cast | John | 64 | |
 Andrew McFarlane | Cast | Actor | 6 | |
Luke Zimmerman | Cast | Actor | Tom Bowman | 1 |
 Leslie Thurston | Cast | Actress | Nurse chief | 1 |
 Chasen Joseph Schneider | Cast | Actor | Joe Hampton | 12 |
 Hudson Thames | Cast | Actor | Brian | 1 |
Lauran Irion | Cast | Actress | Layla | 1 |
 James Di Giacomo | Cast | Actor | Waiter | 1 |
| Person | Type | Job | Role(s) | Episodes |
