Sherlock Holmes in the 22nd Century

Lois St. Clair asks Holmes to find her husband Neville. The investigation leads to a panhandler with a twisted lip.

A man receives five orange seeds, or pips in a letter, but they have been tainted with some kind of serum that induces a coma in him. Before succumbing, he writes down an address and gives his son these instructions. Get help from Sherlock Holmes, and under no circumstances is he to be brought to a hospital. Complicating matters, is the family are ""anti-techs,"" people who are strongly against tecnology and robots of any kind, preferring to live in Sherlock's time period. Watson is not exactly welcome...

Henry Baker loses hat and doll, a GREEN Carbuncle rather than the usual blue one from the Wundygate toy store. It is actually a prototype robot with a human-like personality. Naturally Moriarity wants it. Holmes lets him have it!

Hilton Cubitt and his wife, Elsie, are devloping a way to grow plants at subzero temperatures. But someone wants their research, and he is willing to kill them for it. Someone breaks in and a struggle ensues, ending with Hilton falling into a cryogenic tank and Elsie out cold beside it. Holmes and the gang arrive to help. Not only must they solve the case, but they must also deal with a nosy cousin, Abe Slaney. They end up finding out quite a bit, involving a strange email with a series of dancing stick figure men and Mrs. Cubitt's past.

Fenwick and Moriarty's other henchmen assume disguises, using technology invented by Dr. Blessington to make their DNA unrecognizable.

A mysterious and somewhat theatrical vampire is crashing computer grids, swimping codes, invading locked vaults, and causing panic in New London. The only clue is video images of the devil grinning into the camera as he crushes a computer disk in his hand. Lestrade pursues the Sussex vampire with her usual (destructive) aplomb, which rather amuses the detective. Diedre--who has a unique female perspective on things that Holmes cannot for all his smarts manufacture--notes an interesting quirk their foe has while watching hours of old vamp flicks and tapes of the Sussex vamp's little disk-breaking show. Holmes, Watson, and the Baker St. Irregulars pursue the data-sucking fiend into its sewer lair...and meet up with an old ""friend"" of Holmes', who is also looking into the vamp matter.

A loud argument between a man and his wife attracts the attention of their housekeeper. The man is then discovered to be missing. The room shows signs of a great struggle, with curious parallel slashes everywhere. It also seems that a great change has come over the wife since her walk that afternoon. Holmes is determined to find out what happened on that walk. The result is amazing.

A giant hound has been seen-and strangely enough, heard- on the moon. People are worried. It's up to Holmes, Watson, and Lestrade to expose what's happening and to catch who's responsible for it all. Of course, being jumped by the hound along the way doesn't help matters...

The pilot tells how Holmes survived in and came to be revived in the Holmes Museum. He anticipated two centuries' progress in cryogenics, preserving himself -- in honey! The criminal activity of Moriarty's clone prompts Inspector Lestrad, like her ancestor, to seek Holmes' help. Her compudroid so loves the Canon of Sherlock Holmes stories that it assumes the name and role of Dr. Watson.