| Person | Type | Job | Role(s) | Episodes |
|---|---|---|---|---|
 Duffy Boudreau | Crew | Writing | Writer | 1 |
 Jennifer Flackett | Crew | Writing | Writer, Story, Creator | 1 |
Joel Moser | Crew | Directing | Director | 10 |
 Mark Levin | Crew | Writing | Story, Writer, Creator | 1 |
Peter Knight | Crew | Writing | Writer | 1 |
 Victor Quinaz | Crew | Writing | Writer, Teleplay | 6 |
 Nick Kroll | Crew | Writing | Story, Writer, Creator | 1 |
 Joe Wengert | Crew | Writing | Story, Writer | 1 |
 Max Silvestri | Crew | Writing | Writer | 1 |
 Alex Rubens | Crew | Writing | Writer | 1 |
Andres Salaff | Crew | Directing | Director | 2 |
 Brandon Kyle Goodman | Crew | Writing | Writer | 1 |
 Mitra Jouhari | Crew | Writing | Writer | 1 |
 Andrew Goldberg | Crew | Writing | Story, Writer, Creator | 1 |
Bob Suarez | Crew | Directing | Director | 8 |
 Kelly Galuska | Crew | Writing | Story, Writer | 1 |
 Jak Knight | Crew | Writing | Writer | 2 |
 Jaboukie Young-White | Crew | Writing | Teleplay, Writer | 1 |
 Gil Ozeri | Crew | Writing | Teleplay, Writer | 1 |
Kim Arndt | Crew | Directing | Director | 3 |
 Mike L. Mayfield | Crew | Directing | Director, Writer | 2 |
Joellen Redlingshafer | Crew | Writing | Writer | 1 |
 Patti Harrison | Crew | Writing | Writer | 1 |
Dave Stone | Crew | Directing | Director | 2 |
Bryan Francis | Crew | Directing | Director | 12 |
Jess Dweck | Crew | Writing | Writer | 1 |
Kelsey Cressman | Crew | Writing | Writer | 1 |
Hayley Adams | Crew | Writing | Writer | 1 |
Emily Altman | Crew | Writing | Teleplay, Writer | 1 |
 Charles Bradley | Crew | Sound | Theme Song Performance | 51 |
 Adam Scott | Cast | Actor | Mr. Keating (voice) | 1 |
 Alia Shawkat | Cast | Actress | Roland (voice) | 1 |
 Andy Daly | Cast | Actor | Dr. Wendy Engle (voice) | 1 |
 Andrew Rannells | Cast | Actor | 1 | |
 Anna Graves | Cast | Actress | Mrs. Albert (voice) | 1 |
 Billy Porter | Cast | Actor | Ocean (voice) | 1 |
 Bobby Cannavale | Cast | Actor | Nick's Agent (voice) | 1 |
 Carlos Alazraqui | Cast | Actor | Gustavo (voice) | 2 |
 Carol Kane | Cast | Actress | Menopause Banshee / Old Woman (voice) | 1 |
 Craig Robinson | Cast | Actor | (voice) | 1 |
 David Cross | Cast | Actor | Skip Glouberman (voice) | 1 |
 David Thewlis | Cast | Actor | Shame Wizard (voice) | 8 |
 Don Cheadle | Cast | Actor | Don Cheadle (voice) | 1 |
 Fred Armisen | Cast | Actor | Elliot Birch (voice) | 71 |
 Gary Cole | Cast | Actor | Edward MacDell (voice) | 1 |
 Harvey Fierstein | Cast | Actor | Older Guy Town Resident (voice) | 1 |
 Hugh Jackman | Cast | Actor | himself (voice) | 1 |
 Jean Smart | Cast | Actress | 1 | |
 Jerry Minor | Cast | Actor | Man #3 / Singing Fish (voice) | 1 |
 Jessica Chaffin | Cast | Actress | 1 | |
 John Oliver | Cast | Actor | Harry (voice) | 3 |
 Jon Hamm | Cast | Actor | Scallops (voice) | 1 |
 Judd Hirsch | Cast | Actor | Lewis Glouberman (voice) | 2 |
 Julie White | Cast | Actress | Kimberly MacDell (voice) | 1 |
 Kat Dennings | Cast | Actress | Leah Birch / Lorraine the Hormone Monstress (voice) | 1 |
 Kristen Bell | Cast | Actress | Uninterested Girl (voice) | 1 |
 Lin-Manuel Miranda | Cast | Actor | Puerto Rican Pubic Hair (voice) | 1 |
 Mae Whitman | Cast | Actress | Tallulah Levine (voice) | 1 |
 Maria Bamford | Cast | Actress | 1 | |
 Mark Duplass | Cast | Actor | 1 | |
 Martin Short | Cast | Actor | Gordie (voice) | 1 |
 Maya Rudolph | Cast | Actress | Diane Birch / Constance the Hormone Monstress (voice) | 71 |
 Natasha Lyonne | Cast | Actress | Suzette (voice) | 3 |
 Nathan Fillion | Cast | Actor | Nathan Fillion (voice) | 7 |
 Padma Lakshmi | Cast | Actress | Priya (voice) | 1 |
 Pamela Adlon | Cast | Actress | Sonya the Lovebug (voice) | 1 |
 Patrick Page | Cast | Actor | Dread (voice) | 2 |
 Paul Giamatti | Cast | Actor | Andrew’s Shit (voice) | 1 |
 Paula Pell | Cast | Actress | 1 | |
 Retta | Cast | Actress | Duke's Mother (voice) | 1 |
 Richard Kind | Cast | Actor | Marty Glouberman (voice) | 23 |
 Rosie Perez | Cast | Actress | Petra (voice) | 1 |
 Seth Rogen | Cast | Actor | Seth Goldberg (voice) | 3 |
 Thandiwe Newton | Cast | Actress | Mona (voice) | 4 |
 Wanda Sykes | Cast | Actress | Ghost of Harriet Tubman (voice) | 1 |
 Zach Galifianakis | Cast | Actor | Gratitoad (voice) | 1 |
 Zachary Quinto | Cast | Actor | 1 | |
Brendan McCreary | Cast | Ghost of Freddie Mercury (voice) | 1 | |
 Chelsea Peretti | Cast | Actress | 1 | |
 Gina Rodriguez | Cast | Actress | Gina Alvarez / Gina Parrot (voice) | 1 |
 Jack McBrayer | Cast | Actor | Pubic Hair #1 (voice) | 5 |
 Jason Mantzoukas | Cast | Actor | Jay Bilzerian (voice) | 71 |
 Jemaine Clement | Cast | Actor | Simon Sex (voice) | 1 |
 Jessi Klein | Cast | Actress | Jessi Glaser (voice) | 71 |
 John Gemberling | Cast | Actor | Tyler the Hormone Monster (voice) | 3 |
 John Mulaney | Cast | Actor | Andrew Glouberman (voice) | 71 |
 Jon Daly | Cast | Actor | Garrison Keillor / Magician #1 (voice) | 1 |
 Jordan Peele | Cast | Actor | Ghost of Duke Ellington (voice) | 71 |
 June Diane Raphael | Cast | Actress | Devin (voice) | 18 |
 Keke Palmer | Cast | Actress | Rochelle the Hate Worm (voice) | 1 |
 Kristen Schaal | Cast | Actress | Bernie Sanders (voice) | 1 |
 Kristen Wiig | Cast | Actress | Jessi's Vagina (voice) | 3 |
 Lupita Nyong'o | Cast | Actress | Asha (voice) | 1 |
 Michaela Watkins | Cast | Actress | Cantor Dina Reznick (voice) | 5 |
 Nasim Pedrad | Cast | Actress | Fatima (voice) | 1 |
Nick Kroll | Cast | Actor | Nick Birch / Maury the Hormone Monster / Coach Steve (voice) | 71 |
 Paul Scheer | Cast | Actor | 1 | |
 Philip Quinaz | Cast | Actor | Tanya Alvarez (voice) | 1 |
 Randall Park | Cast | Actor | Pete Doheny (voice) | 1 |
 Rob Huebel | Cast | Actor | Mr. Lizer (voice) | 6 |
 Rob Riggle | Cast | Actor | Sgt. Adderall (voice) | 1 |
 Seth Morris | Cast | Actor | (voice) | 2 |
 Sterling K. Brown | Cast | Actor | 1 | |
 Zach Woods | Cast | Actor | Sock (voice) | 1 |
 Beck Bennett | Cast | Actor | Owen (voice) | 2 |
 Heather Lawless | Cast | Actress | Jenna Bilzerian (voice) | 11 |
 Jenny Slate | Cast | Actress | Missy Foreman-Greenwald (voice) | 41 |
Joe Wengert | Cast | Caleb / Go-Gurt Burglar (voice) | 1 | |
 Jon Gabrus | Cast | Actor | Movie Theater Customer (voice) | 1 |
 Lena Waithe | Cast | Actress | Lena (voice) | 2 |
 Neil Casey | Cast | Actor | Detective Dumont / Lars (voice) | 1 |
 Piotr Michael | Cast | Actor | Siamese Twin #2 (voice) | 1 |
 Ali Wong | Cast | Actress | 1 | |
 Kumail Nanjiani | Cast | Actor | himself (voice) | 1 |
 Maya Erskine | Cast | Actress | Misha (voice) | 1 |
 Miranda Tapsell | Cast | Actress | Kara (voice) | 1 |
 Rosa Salazar | Cast | Actress | Ms. Benitez (voice) | 4 |
 Stephanie Beatriz | Cast | Actress | Lulu (voice) | 3 |
 Aidy Bryant | Cast | Actress | Emmy (voice) | 1 |
 Anna Konkle | Cast | Actress | Izzy (voice) | 1 |
 Ayden Mayeri | Cast | Actress | Gabrielle / Sad Boy #2 (voice) | 1 |
 Chris Redd | Cast | Actor | (voice) | 2 |
 Josie Totah | Cast | Actress | Natalie (voice) | 2 |
Brandon Kyle Goodman | Cast | Actor | Walter the Lovebug (voice) | 10 |
 Bobby Berk | Cast | Actor | Bobby Berk (voice) | 1 |
 Julie Klausner | Cast | Cherry Marashina (voice) | 2 | |
 Ayo Edebiri | Cast | Actress | Missy Foreman-Greenwald / Mosaic Missy (voice) | 1 |
 Tawny Newsome | Cast | Actress | (voice) | 1 |
 Jonathan van Ness | Cast | Jonathan Van Ness (voice) | 1 | |
Jak Knight | Cast | Actor | DeVon | 1 |
Jaboukie Young-White | Cast | Actor | (voice) | 1 |
 Karamo Brown | Cast | Actor | Karamo Brown (voice) | 1 |
Gil Ozeri | Cast | (voice) | 2 | |
 Antoni Porowski | Cast | Actor | Antoni Porowski (voice) | 1 |
Mark Rivers | Cast | Ghost of David Bowie (voice) | 1 | |
 Tan France | Cast | Tan France (voice) | 1 | |
 Fran Gillespie | Cast | Maddie the American Girl Doll / Choir Girl (voice) | 1 | |
 Quinta Brunson | Cast | Actress | Quinta (voice) | 2 |
 Joel Kim Booster | Cast | Actor | Charles Lu (voice) | 2 |
 Megan Thee Stallion | Cast | Actress | Megan the(e?) Hormone Monstress (voice) | 3 |
Chloe Fineman | Cast | Actress | Leah Birch (voice) | 2 |
Ashley London | Cast | Actress | The Virgin Mary / Waitress (voice) | 1 |
Crissy Guerrero | Cast | (voice) | 1 | |
Marisa Lark Wallin | Cast | Reese's Wertherspoon / Woman (voice) | 1 | |
Chrissy Guerrero | Cast | Choir Girl (voice) | 1 | |
Ileen Goldsmith | Cast | Jessi Glaser - singing double / Judd's Girlfriend (voice) | 1 | |
 Maitreyi Ramakrishnan | Cast | Actress | Marissa (voice) | 1 |
Emily Altman | Cast | Milk (voice) | 2 | |
 Somali Rose | Cast | Missy’s Overalls | 1 | |
| Person | Type | Job | Role(s) | Episodes |
