| Person | Type | Job | Role(s) |
|---|---|---|---|
 Caroline Hanania | Crew | Art | Production Design |
 George C. Wolfe | Crew | Writing | Screenplay, Director |
Aaron Yanes | Crew | Editing | Editor |
 Alexander Woo | Crew | Writing | Writer |
 Cindy Tolan | Crew | Production | Casting |
 Peter Landesman | Crew | Writing | Adaptation |
 Sofian El Fani | Crew | Camera | Director of Photography |
 Mateo Márquez | Crew | Editing | Digital Intermediate Assistant |
Rebecca Skloot | Crew | Writing | Book |
 Paul Tazewell | Crew | Costume & Make-Up | Costume Design |
 Alpha Trivette | Cast | Actor | First Administrator |
 Courtney B. Vance | Cast | Actor | Sir Lord Keenan Coefield |
 Earl Poitier | Cast | Actor | Cousin Josh |
 L. Warren Young | Cast | Actor | Day Lacks |
 Lisa Arrindell | Cast | Actress | Aunt Ethel |
 Oprah Winfrey | Cast | Actress | Deborah Lacks |
 Reed Birney | Cast | Actor | Dr. George Gey |
 Reg E. Cathey | Cast | Actor | Zakariyyah |
 Renée Elise Goldsberry | Cast | Actress | Henrietta Lacks |
 Rose Byrne | Cast | Actress | Rebecca Skloot |
 Tinashe Kajese | Cast | Actress | Sadie |
 Jane Rumbaua | Cast | Actress | Mrs. Hsu |
 Ninja N. Devoe | Cast | Actress | Country Girl Mae |
Jaedon Godley | Cast | Davon Lacks | |
 Karen Wheeling Reynolds | Cast | Actress | Mrs. Gey |
 Kate Bond | Cast | Actress | Young Woman |
 Sylvia Grace Crim | Cast | Actress | Mary Kubicek |
 Tatom Pender | Cast | Actress | Johns Hopkins Nurse |
 Kyanna Simone Simpson | Cast | Actress | Deborah (15-24YRS) |
 Mary Shaw | Cast | Woman at Pump | |
Todd Lee | Cast | Doctor | |
De'Marco Arrington | Cast | Young Joe | |
 Jaylon Gordon | Cast | Alfred | |
Jazzy Ellis | Cast | Actress | Young Gladys |
 Jock McKissic | Cast | Actor | Carl the Mechanic |
 Patrick Walker | Cast | Actor | Cousin Fred |
Christopher Robert Escobar | Cast | Chris the Intern | |
Clint Edwards | Cast | Scientist | |
Elizabeth Hackler | Cast | Rebecca's Co-worker | |
 Jordan Eli Arellano | Cast | Young Sonny Lacks | |
Kayla Anderson | Cast | Johns Hopkins Student | |
Matthew Bernard | Cast | Johns Hopkins Student | |
Miguel Angel Marrero | Cast | Scientist | |
Tashaun Stanfill-Perry | Cast | Henrietta Lacks Neighbor | |
 Tian Richards | Cast | Actor | Lawrence (16 yrs.) |
Raphael Dante' Carr Jr. | Cast | Actor | Young Sonny |
 Sage Mayer | Cast | Actor | Young Boy |
Tyvonna Jones | Cast | Elsie Lacks | |
 David Shae | Cast | Actor | Reporter |
Sean Freeland | Cast | Actor | Charlie |
 Gabriel Ebert | Cast | Actor | Christoph Lengauer |
Terrence V. Walker | Cast | Church Patron | |
 Kent Wagner | Cast | Actor | Scientist (uncredited) |
| Person | Type | Job | Role(s) |
