| Person | Type | Job | Role(s) |
|---|---|---|---|
 Alec Hammond | Crew | Art | Production Design |
Alec Sokolow | Crew | Writing | Screenplay |
 Barbara Anne Klein | Crew | Crew | Stunts |
Brian Manis | Crew | Production | Executive Producer |
 Christophe Beck | Crew | Sound | Original Music Composer |
 Dean Cundey | Crew | Camera | Director of Photography |
 Glenn Derry | Crew | Visual Effects | Pre-Visualization Supervisor |
 Jim Davis | Crew | Writing | Comic Book |
 Joel Cohen | Crew | Writing | Screenplay |
 John Davis | Crew | Production | Producer |
Marie France | Crew | Costume & Make-Up | Costume Design |
Michael A. Stevenson | Crew | Editing | Editor |
Michele Imperato Stabile | Crew | Production | Co-Producer |
Neil Machlis | Crew | Production | Executive Producer |
Peter E. Berger | Crew | Editing | Editor |
 Peter Hewitt | Crew | Directing | Director |
 Risa Bramon Garcia | Crew | Production | Casting |
Angie Jones | Crew | Visual Effects | Animation |
Mathew Krentz | Crew | Visual Effects | Compositing Artist |
 Dan DeLeeuw | Crew | Visual Effects | Visual Effects Supervisor |
Brennan Dufresne | Crew | Production | Casting |
 Alan Cumming | Cast | Actor | Persnikitty (voice) |
 Bill Hoag | Cast | Actor | Roy the Lodge Member |
 Bill Murray | Cast | Actor | Garfield (voice) |
 Brad Garrett | Cast | Actor | Luca (voice) |
 Breckin Meyer | Cast | Actor | Jon |
 Daamen J. Krall | Cast | Actor | Announcer |
 David Eigenberg | Cast | Actor | Nermal (voice) |
 Debra Messing | Cast | Actress | Arlene (voice) |
 Evan Arnold | Cast | Actor | Wendell |
 Eve Brent | Cast | Actress | Mrs. Baker |
 Jennifer Love Hewitt | Cast | Actress | Liz |
 Jerry Hauck | Cast | Actor | Cop |
 Jimmy Kimmel | Cast | Actor | Spanky (voice) |
 Mark Christopher Lawrence | Cast | Actor | Christopher Mello |
 Mel Rodriguez | Cast | Actor | Security Officer |
 Michael Monks | Cast | Actor | Deputy Hopkins |
 Nick Cannon | Cast | Actor | Louis (voice) |
 Richard Kind | Cast | Actor | Dad Rat (voice) |
 Rufus Gifford | Cast | Actor | Dog Owner #1 |
 Stephen Tobolowsky | Cast | Actor | Happy Chapman |
 Vanessa Campbell | Cast | Actress | Miss Ace Hardware |
 Alyson Stoner | Cast | Kid Rat (voice) | |
 Juliette Goglia | Cast | Actress | Little Girl |
 Randee Reicher | Cast | Actress | Dog Owner #2 |
Susan Moore | Cast | Dog Owner #4 | |
Ryan McKasson | Cast | Dog Owner #3 | |
 Ben Kronen | Cast | Actor | Older Man |
 Joseph Edward Taylor | Cast | Actor | Frank |
| Person | Type | Job | Role(s) |
